Phosphonoacetic Acid-Resistant Mutants of Herpes Simplex Virus: Effect of Phosphonoacetic Acid on Virus Replication and In Vitro Deoxyribonucleic Acid Synthesis in Isolated Nuclei

Phosphonoacetic acid (PAA) inhibits the replication of herpes simplex virus in BSC-1 cells and the in vitro synthesis of deoxyribonucleic acid (DNA) in isolated nuclei. Phosphonopropionic acid at a concentration of 100 μg/ml had no effect on herpes simplex virus replication. PAA-resistant mutants we...

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Main Authors: Becker, Yechiel, Asher, Yael, Cohen, Yaffa, Weinberg-Zahlering, Eynat, Shlomai, Joseph
Format: Artigo
Jezik:Inglês
Izdano: 1977
Teme:
Biosynthesis: Chemistry; Mechanisms of Action and Resistance
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC352099/
https://ncbi.nlm.nih.gov/pubmed/195514
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