Phosphonoacetic Acid-Resistant Mutants of Herpes Simplex Virus: Effect of Phosphonoacetic Acid on Virus Replication and In Vitro Deoxyribonucleic Acid Synthesis in Isolated Nuclei

Phosphonoacetic acid (PAA) inhibits the replication of herpes simplex virus in BSC-1 cells and the in vitro synthesis of deoxyribonucleic acid (DNA) in isolated nuclei. Phosphonopropionic acid at a concentration of 100 μg/ml had no effect on herpes simplex virus replication. PAA-resistant mutants we...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Becker, Yechiel, Asher, Yael, Cohen, Yaffa, Weinberg-Zahlering, Eynat, Shlomai, Joseph
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1977
Fag:	Biosynthesis: Chemistry; Mechanisms of Action and Resistance
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352099/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/195514/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.11.5.919
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