Chronic Exposure to Nicotine Enhances Insulin Sensitivity through α7 Nicotinic Acetylcholine Receptor-STAT3 Pathway

This study was to investigate the effect of nicotine on insulin sensitivity and explore the underlying mechanisms. Treatment of Sprague-Dawley rats with nicotine (3 mg/kg/day) for 6 weeks reduced 43% body weight gain and 65% blood insulin level, but had no effect on blood glucose level. Both insulin...

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Detalhes bibliográficos
Main Authors: Xu, Tian-Ying, Guo, Ling-Ling, Wang, Pei, Song, Jie, Le, Ying-Ying, Viollet, Benoit, Miao, Chao-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520975/
https://ncbi.nlm.nih.gov/pubmed/23251458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051217
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