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Nicotine exposure and the progression of chronic kidney disease: role of the α7-nicotinic acetylcholine receptor

Clinical studies have established the role of cigarette smoking as a risk factor in the progression of chronic kidney disease (CKD). We have shown that nicotine promotes mesangial cell proliferation and hypertrophy via nonneuronal nicotinic acetylcholine receptors (nAChRs). The α7-nAChR is one of th...

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Autori principali: Rezonzew, Gabriel, Chumley, Phillip, Feng, Wenguang, Hua, Ping, Siegal, Gene P., Jaimes, Edgar A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404588/
https://ncbi.nlm.nih.gov/pubmed/22552933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00661.2011
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