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Transduction of Skeletal Muscles with Common Reporter Genes Can Promote Muscle Fiber Degeneration and Inflammation

Recombinant adeno-associated viral vectors (rAAV vectors) are promising tools for delivering transgenes to skeletal muscle, in order to study the mechanisms that control the muscle phenotype, and to ameliorate diseases that perturb muscle homeostasis. Many studies have employed rAAV vectors carrying...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Winbanks, Catherine E., Beyer, Claudia, Qian, Hongwei, Gregorevic, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520959/
https://ncbi.nlm.nih.gov/pubmed/23251598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051627
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