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Expression and significance of histone H3K27 demethylases in renal cell carcinoma

BACKGROUND: The histone H3K27 demethylases UTX and JMJD3 are important regulatory factors that modulate gene expression by altering the physical state of chromatin. Previous studies have indicated an abnormal H3K27 methylation status in carcinogenesis. We therefore investigated the expression patter...

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Detalhes bibliográficos
Main Authors: Shen, Yongqing, Guo, Xiaoqiang, Wang, Yuejia, Qiu, Wei, Chang, Yanzhong, Zhang, Aili, Duan, Xianglin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520868/
https://ncbi.nlm.nih.gov/pubmed/23057811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-470
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