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Inhibition of the histone H3K27 demethylase UTX enhances tumor cell radiosensitivity

The processes mediating the repair of DNA double strand breaks (DSBs) are critical determinants of radiosensitivity and provide a source of potential targets for tumor radiosensitization. Among the events required for efficient DSB repair are a variety of post-translational histone modifications inc...

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發表在:Mol Cancer Ther
Main Authors: Rath, Barbara H., Waung, Isabella, Camphausen, Kevin, Tofilon, Philip J.
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932086/
https://ncbi.nlm.nih.gov/pubmed/29483212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-1053
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