Loading...

Inhibition of the histone H3K27 demethylase UTX enhances tumor cell radiosensitivity

The processes mediating the repair of DNA double strand breaks (DSBs) are critical determinants of radiosensitivity and provide a source of potential targets for tumor radiosensitization. Among the events required for efficient DSB repair are a variety of post-translational histone modifications inc...

Full description

Saved in:
Bibliographic Details
Published in:Mol Cancer Ther
Main Authors: Rath, Barbara H., Waung, Isabella, Camphausen, Kevin, Tofilon, Philip J.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932086/
https://ncbi.nlm.nih.gov/pubmed/29483212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-1053
Tags: Add Tag
No Tags, Be the first to tag this record!