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Structural basis of specific interactions of Lp-PLA(2) with HDL revealed by hydrogen deuterium exchange mass spectrometry

Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)), specifically Group VIIA PLA(2), is a member of the phospholipase A(2) superfamily and is found mainly associated with LDL and HDL in human plasma. Lp-PLA(2) is considered as a risk factor, a potential biomarker, a target for therapy in the treat...

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Bibliographic Details
Main Authors: Cao, Jian, Hsu, Yuan-Hao, Li, Sheng, Woods, Virgil L., Dennis, Edward A.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520519/
https://ncbi.nlm.nih.gov/pubmed/23089916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M030221
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