ChAd63-MVA–vectored Blood-stage Malaria Vaccines Targeting MSP1 and AMA1: Assessment of Efficacy Against Mosquito Bite Challenge in Humans

The induction of cellular immunity, in conjunction with antibodies, may be essential for vaccines to protect against blood-stage infection with the human malaria parasite Plasmodium falciparum. We have shown that prime-boost delivery of P. falciparum blood-stage antigens by chimpanzee adenovirus 63...

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Detalhes bibliográficos
Main Authors: Sheehy, Susanne H, Duncan, Christopher JA, Elias, Sean C, Choudhary, Prateek, Biswas, Sumi, Halstead, Fenella D, Collins, Katharine A, Edwards, Nick J, Douglas, Alexander D, Anagnostou, Nicholas A, Ewer, Katie J, Havelock, Tom, Mahungu, Tabitha, Bliss, Carly M, Miura, Kazutoyo, Poulton, Ian D, Lillie, Patrick J, Antrobus, Richard D, Berrie, Eleanor, Moyle, Sarah, Gantlett, Katherine, Colloca, Stefano, Cortese, Riccardo, Long, Carole A, Sinden, Robert E, Gilbert, Sarah C, Lawrie, Alison M, Doherty, Tom, Faust, Saul N, Nicosia, Alfredo, Hill, Adrian VS, Draper, Simon J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519995/
https://ncbi.nlm.nih.gov/pubmed/23089736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.223
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