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Phase Ia Clinical Evaluation of the Plasmodium falciparum Blood-stage Antigen MSP1 in ChAd63 and MVA Vaccine Vectors

Efficacy trials of antibody-inducing protein-in-adjuvant vaccines targeting the blood-stage Plasmodium falciparum malaria parasite have so far shown disappointing results. The induction of cell-mediated responses in conjunction with antibody responses is thought to be one alternative strategy that c...

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Detalhes bibliográficos
Main Authors: Sheehy, Susanne H, Duncan, Christopher JA, Elias, Sean C, Collins, Katharine A, Ewer, Katie J, Spencer, Alexandra J, Williams, Andrew R, Halstead, Fenella D, Moretz, Samuel E, Miura, Kazutoyo, Epp, Christian, Dicks, Matthew DJ, Poulton, Ian D, Lawrie, Alison M, Berrie, Eleanor, Moyle, Sarah, Long, Carole A, Colloca, Stefano, Cortese, Riccardo, Gilbert, Sarah C, Nicosia, Alfredo, Hill, Adrian VS, Draper, Simon J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242658/
https://ncbi.nlm.nih.gov/pubmed/21862998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.176
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