Targeting TCTP as a New Therapeutic Strategy in Castration-resistant Prostate Cancer

Heat shock protein 27 (Hsp27) is highly overexpressed in castration-resistant prostate cancer (CRPC) and an antisense inhibitor (OGX-427) is currently in phase II clinical trials. In order to understand mechanisms of action of Hsp27 and find new therapeutic targets specific of CRPC, we screened for...

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Autors principals: Baylot, Virginie, Katsogiannou, Maria, Andrieu, Claudia, Taieb, David, Acunzo, Julie, Giusiano, Sophie, Fazli, Ladan, Gleave, Martin, Garrido, Carmen, Rocchi, Palma
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519986/
https://ncbi.nlm.nih.gov/pubmed/22893039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.155
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