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Smac Mimetic SM-164 Potentiates APO2L/TRAIL- and Doxorubicin-Mediated Anticancer Activity in Human Hepatocellular Carcinoma Cells
BACKGROUND: The members of inhibitor of apoptosis proteins (IAPs) family are key negative regulators of apoptosis. Overexpression of IAPs are found in hepatocellular carcinoma (HCC), and can contribute to chemotherapy resistance and recurrence of HCC. Small-molecule Second mitochondria-derived activ...
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Autors principals: | , , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Public Library of Science
2012
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3519882/ https://ncbi.nlm.nih.gov/pubmed/23240027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051461 |
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