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Increasing Hippocampal Estrogen Receptor Alpha Levels via Viral Vectors Increases MAP Kinase Activation and Enhances Memory in Aging Rats in the Absence of Ovarian Estrogens

We previously demonstrated that aged ovariectomized rats that had received prior estradiol treatment in middle-age exhibited increased levels of estrogen receptor alpha (ERα) in the hippocampus as well as enhanced hippocampal dependent memory as compared to aged rats that had not received mid-life e...

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Hlavní autoři: Witty, Christine F., Foster, Thomas C., Semple-Rowland, Susan L., Daniel, Jill M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519866/
https://ncbi.nlm.nih.gov/pubmed/23240018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051385
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