Pregnenolone Rescues Schizophrenia-Like Behavior in Dopamine Transporter Knockout Mice

Pregnenolone belongs to a class of endogenous neurosteroids in the central nervous system (CNS), which has been suggested to enhance cognitive functions through GABA(A) receptor signaling by its metabolites. It has been shown that the level of pregnenolone is altered in certain brain areas of schizo...

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Main Authors: Wong, Peiyan, Chang, Cecilia Chin Roei, Marx, Christine E., Caron, Marc G., Wetsel, William C., Zhang, Xiaodong
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519851/
https://ncbi.nlm.nih.gov/pubmed/23240026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051455
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