ATM Suppresses SATB1-Induced Malignant Progression in Breast Epithelial Cells

SATB1 drives metastasis when expressed in breast tumor cells by radically reprogramming gene expression. Here, we show that SATB1 also has an oncogenic activity to transform certain non-malignant breast epithelial cell lines. We studied the non-malignant MCF10A cell line, which is used widely in the...

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Hlavní autoři: Ordinario, Ellen, Han, Hye-Jung, Furuta, Saori, Heiser, Laura M., Jakkula, Lakshmi R., Rodier, Francis, Spellman, Paul T., Campisi, Judith, Gray, Joe W., Bissell, Mina J., Kohwi, Yoshinori, Kohwi-Shigematsu, Terumi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519734/
https://ncbi.nlm.nih.gov/pubmed/23251624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051786
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