ATM Suppresses SATB1-Induced Malignant Progression in Breast Epithelial Cells

SATB1 drives metastasis when expressed in breast tumor cells by radically reprogramming gene expression. Here, we show that SATB1 also has an oncogenic activity to transform certain non-malignant breast epithelial cell lines. We studied the non-malignant MCF10A cell line, which is used widely in the...

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Detalhes bibliográficos
Main Authors: Ordinario, Ellen, Han, Hye-Jung, Furuta, Saori, Heiser, Laura M., Jakkula, Lakshmi R., Rodier, Francis, Spellman, Paul T., Campisi, Judith, Gray, Joe W., Bissell, Mina J., Kohwi, Yoshinori, Kohwi-Shigematsu, Terumi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519734/
https://ncbi.nlm.nih.gov/pubmed/23251624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051786
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