EGFR-dependent downregulation of Capicua and the establishment of Drosophila dorsoventral polarity

Dorsoventral (DV) axis formation in Drosophila begins during oogenesis through the graded activation of the EGF receptor (EGFR)-Ras-MAPK signaling pathway in the follicle cell layer of the egg chamber. EGFR signaling, which is higher in dorsal follicle cells, represses expression of the sulfotransfe...

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Autores principales: Andreu, María José, Ajuria, Leiore, Samper, Núria, González-Pérez, Esther, Campuzano, Sonsoles, González-Crespo, Sergio, Jiménez, Gerardo
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519657/
https://ncbi.nlm.nih.gov/pubmed/22878648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/fly.21160
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