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Bone Marrow Toxicity Associated with 5-Fluorocytosine Therapy

Bone marrow toxicity occurred in 4 of 15 patients treated with 5-fluorocytosine (5-FC) for serious fungal infections. The development of marrow toxicity appeared to be related to serum 5-FC levels of 125 μg/ml or greater. In three patients, accumulation of toxic levels of 5-FC was related to diminis...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Kauffman, Carol A., Frame, Peter T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC351961/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/848928/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.11.2.244
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