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Bone Marrow Toxicity Associated with 5-Fluorocytosine Therapy

Bone marrow toxicity occurred in 4 of 15 patients treated with 5-fluorocytosine (5-FC) for serious fungal infections. The development of marrow toxicity appeared to be related to serum 5-FC levels of 125 μg/ml or greater. In three patients, accumulation of toxic levels of 5-FC was related to diminis...

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Bibliographic Details
Main Authors: Kauffman, Carol A., Frame, Peter T.
Format: Artigo
Language:Inglês
Published: 1977
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC351961/
https://ncbi.nlm.nih.gov/pubmed/848928
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