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A high-performance computing toolset for relatedness and principal component analysis of SNP data

Summary: Genome-wide association studies are widely used to investigate the genetic basis of diseases and traits, but they pose many computational challenges. We developed gdsfmt and SNPRelate (R packages for multi-core symmetric multiprocessing computer architectures) to accelerate two key computat...

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Main Authors: Zheng, Xiuwen, Levine, David, Shen, Jess, Gogarten, Stephanie M., Laurie, Cathy, Weir, Bruce S.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519454/
https://ncbi.nlm.nih.gov/pubmed/23060615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts606
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