Phase I Clinical Trial of O6-Benzylguanine and Topical Carmustine in the Treatment of Cutaneous T-Cell Lymphoma, Mycosis Fungoides Type

OBJECTIVES: To evaluate the toxic effects and maximum tolerated dose of topical carmustine [1,3-bis (2-chloroethyl)-1-nitrosourea] following intravenous O6-benzylguanine in the treatment of cutaneous T-cell lymphoma (CTCL), and to determine pharmacodynamics of O6-alkylguanine DNA alkyltransferase ac...

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Detalhes bibliográficos
Main Authors: Apisarnthanarax, Narin, Wood, Gary S., Stevens, Seth R., Carlson, Sean, Chan, Derek V., Liu, Lili, Szabo, Sarolta K., Fu, Pingfu, Gilliam, Anita C., Gerson, Stanton L., Remick, Scot C., Cooper, Kevin D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519426/
https://ncbi.nlm.nih.gov/pubmed/22250189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archdermatol.2011.2797
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