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CADASIL mutations and shRNA silencing of NOTCH3 affect actin organization in cultured vascular smooth muscle cells

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common hereditary vascular dementia caused by mutations in NOTCH3 gene. Pathology is manifested in small- and middle-sized arteries throughout the body, though primarily in cerebral white...

詳細記述

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書誌詳細
主要な著者: Tikka, Saara, Peng Ng, Yan, Di Maio, Giuseppe, Mykkänen, Kati, Siitonen, Maija, Lepikhova, Tatiana, Pöyhönen, Minna, Viitanen, Matti, Virtanen, Ismo, Kalimo, Hannu, Baumann, Marc
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519411/
https://ncbi.nlm.nih.gov/pubmed/22948298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.123
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