Glucagon-like peptide-1 decreases intracerebral glucose content by activating hexokinase and changing glucose clearance during hyperglycemia

Type 2 diabetes and hyperglycemia with the resulting increase of glucose concentrations in the brain impair the outcome of ischemic stroke, and may increase the risk of developing Alzheimer's disease (AD). Reports indicate that glucagon-like peptide-1 (GLP-1) may be neuroprotective in models of...

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Bibliografiske detaljer
Main Authors: Gejl, Michael, Egefjord, Lærke, Lerche, Susanne, Vang, Kim, Bibby, Bo Martin, Holst, Jens Juul, Mengel, Annette, Møller, Niels, Rungby, Jørgen, Brock, Birgitte, Gjedde, Albert
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519409/
https://ncbi.nlm.nih.gov/pubmed/22929437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.118
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