Glucagon-like peptide-1 decreases intracerebral glucose content by activating hexokinase and changing glucose clearance during hyperglycemia

Type 2 diabetes and hyperglycemia with the resulting increase of glucose concentrations in the brain impair the outcome of ischemic stroke, and may increase the risk of developing Alzheimer's disease (AD). Reports indicate that glucagon-like peptide-1 (GLP-1) may be neuroprotective in models of...

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Detalhes bibliográficos
Main Authors: Gejl, Michael, Egefjord, Lærke, Lerche, Susanne, Vang, Kim, Bibby, Bo Martin, Holst, Jens Juul, Mengel, Annette, Møller, Niels, Rungby, Jørgen, Brock, Birgitte, Gjedde, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519409/
https://ncbi.nlm.nih.gov/pubmed/22929437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.118
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