Calcineurin activation causes retinal ganglion cell degeneration

PURPOSE: We previously reported that calcineurin, a Ca(2+)/calmodulin-dependent serine/threonine phosphatase, is activated and proposed that it participates in retinal ganglion cell (RGC) apoptosis in two rodent ocular hypertension models. In this study, we tested whether calcineurin activation by i...

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Bibliografiske detaljer
Main Authors: Qu, Juan, Matsouaka, Roland, Betensky, Rebecca A., Hyman, Bradley T., Grosskreutz, Cynthia L.
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Vision 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519372/
https://ncbi.nlm.nih.gov/pubmed/23233785
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