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Calcineurin activation causes retinal ganglion cell degeneration

PURPOSE: We previously reported that calcineurin, a Ca(2+)/calmodulin-dependent serine/threonine phosphatase, is activated and proposed that it participates in retinal ganglion cell (RGC) apoptosis in two rodent ocular hypertension models. In this study, we tested whether calcineurin activation by i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qu, Juan, Matsouaka, Roland, Betensky, Rebecca A., Hyman, Bradley T., Grosskreutz, Cynthia L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Vision 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519372/
https://ncbi.nlm.nih.gov/pubmed/23233785
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