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Calcineurin activation causes retinal ganglion cell degeneration

PURPOSE: We previously reported that calcineurin, a Ca(2+)/calmodulin-dependent serine/threonine phosphatase, is activated and proposed that it participates in retinal ganglion cell (RGC) apoptosis in two rodent ocular hypertension models. In this study, we tested whether calcineurin activation by i...

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Detalhes bibliográficos
Main Authors: Qu, Juan, Matsouaka, Roland, Betensky, Rebecca A., Hyman, Bradley T., Grosskreutz, Cynthia L.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519372/
https://ncbi.nlm.nih.gov/pubmed/23233785
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