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Position-dependent Function for a Tandem MicroRNA miR-122 Binding Site Located in the Hepatitis C Virus RNA Genome
MicroRNAs usually interact with 3’ noncoding regions of target mRNAs leading to downregulation of mRNA expression. In contrast, liver-specific microRNA miR-122 is known to interact with the 5’ end of the hepatitis C virus RNA genome, resulting in increased viral RNA abundance. We found that the loca...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3519368/ https://ncbi.nlm.nih.gov/pubmed/18621012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2008.05.013 |
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