Comparison of the Binding Properties of Two 6β-Amidinopenicillanic Acid Derivatives That Differ in Their Physiological Effects on Escherichia coli

The 6-β-amidinopenicillanic acid derivative, mecillinam, was highly specific in its action on the growth of Escherichia coli. Concentrations from the minimal inhibitory concentration (0.05 μg/ml) up to at least 200 μg/ml resulted in the conversion of E. coli rods into osmotically stable spherical ce...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Antimicrob Agents Chemother
1. Verfasser:	Spratt, Brian G.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1977
Schlagworte:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC351936/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/189683/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.11.1.161
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