New Cephamycin Antibiotic, CS-1170: Binding Affinity to Penicillin-Binding Proteins and Inhibition of Peptidoglycan Cross-Linking Reactions in Escherichia coli

The binding activity of CS-1170, a new cephamycin antibiotic, to penicillin-binding proteins (PBPs) in Escherichia coli and Proteus species and the potency of this antibiotic in vitro to inhibit enzymes involved in peptidoglycan cross-linking in E. coli were tested. Similar experiments were carried...

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Autores principales: Ohya, Satoshi, Yamazaki, Mitsuo, Sugawara, Shinichi, Tamaki, Shigeo, Matsuhashi, Michio
Formato: Artigo
Lenguaje:Inglês
Publicado: 1978
Materias:
Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC352550/
https://ncbi.nlm.nih.gov/pubmed/365089
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