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Stable Synthetic Bacteriochlorins for Photodynamic Therapy: Role of Dicyano Peripheral Groups, Central Metal Substitution (2H, Zn, Pd), and Cremophor EL Delivery

A series of four stable synthetic bacteriochlorins was tested in vitro in HeLa cells for their potential in photodynamic therapy (PDT). The parent bacteriochlorin (BC), dicyano derivative (NC)(2)BC and corresponding zinc chelate (NC)(2)BC–Zn and palladium chelate (NC)(2)BC–Pd were studied. Direct di...

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書誌詳細
主要な著者: Huang, Ying-Ying, Balasubramanian, Thiagarajan, Yang, Eunkyung, Luo, Dianzhong, Diers, James R., Bocian, David F., Lindsey, Jonathan S., Holten, Dewey, Hamblin, Michael R.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519240/
https://ncbi.nlm.nih.gov/pubmed/23065820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201200351
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