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Bioassay Method for Polyene Antibiotics Based on the Measurement of Rubidium Efflux from Rubidium-Loaded Yeast Cells

A bioassay method for the polyene antibiotics nystatin and amphotericin B is proposed based on the measurement of the efflux of rubidium ions from a rubidium-loaded yeast culture challenged with the antibiotics. For this purpose a major proportion of the intracellular K(+) ions in a Saccharomyces ce...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Cosgrove, R. F., Fairbrother, J. E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC351913/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/319752/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.11.1.31
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