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Bioassay Method for Polyene Antibiotics Based on the Measurement of Rubidium Efflux from Rubidium-Loaded Yeast Cells

A bioassay method for the polyene antibiotics nystatin and amphotericin B is proposed based on the measurement of the efflux of rubidium ions from a rubidium-loaded yeast culture challenged with the antibiotics. For this purpose a major proportion of the intracellular K(+) ions in a Saccharomyces ce...

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Autors principals: Cosgrove, R. F., Fairbrother, J. E.
Format: Artigo
Idioma:Inglês
Publicat: 1977
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC351913/
https://ncbi.nlm.nih.gov/pubmed/319752
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