β-1,3-Glucan, Which Can Be Targeted by Drugs, Forms a Trabecular Scaffold in the Oocyst Walls of Toxoplasma and Eimeria

The walls of infectious pathogens, which are essential for transmission, pathogenesis, and diagnosis, contain sugar polymers that are defining structural features, e.g., β-1,3-glucan and chitin in fungi, chitin in Entamoeba cysts, β-1,3-GalNAc in Giardia cysts, and peptidoglycans in bacteria. The go...

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Main Authors: Bushkin, G. Guy, Motari, Edwin, Magnelli, Paula, Gubbels, Marc-Jan, Dubey, Jitender P., Miska, Katarzyna B., Bullitt, Esther, Costello, Catherine E., Robbins, Phillips W., Samuelson, John
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Microbiology 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518913/
https://ncbi.nlm.nih.gov/pubmed/23015739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00258-12
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