β-1,3-Glucan, Which Can Be Targeted by Drugs, Forms a Trabecular Scaffold in the Oocyst Walls of Toxoplasma and Eimeria

The walls of infectious pathogens, which are essential for transmission, pathogenesis, and diagnosis, contain sugar polymers that are defining structural features, e.g., β-1,3-glucan and chitin in fungi, chitin in Entamoeba cysts, β-1,3-GalNAc in Giardia cysts, and peptidoglycans in bacteria. The go...

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Detalhes bibliográficos
Main Authors: Bushkin, G. Guy, Motari, Edwin, Magnelli, Paula, Gubbels, Marc-Jan, Dubey, Jitender P., Miska, Katarzyna B., Bullitt, Esther, Costello, Catherine E., Robbins, Phillips W., Samuelson, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518913/
https://ncbi.nlm.nih.gov/pubmed/23015739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00258-12
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