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Context and location dependence of adaptive Foxp3(+) regulatory T cell formation during immunopathological conditions

Circulating Foxp3(+) regulatory T cells (Treg) may arise in the thymus (natural Treg, nTreg) or through the adaptive upregulation of Foxp3 after T cell activation (induced Treg, iTreg). In this brief review, we explore evidence for the formation and function of iTreg during pathologic conditions. De...

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Detalhes bibliográficos
Main Authors: Heiber, Joshua F., Geiger, Terrence L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518695/
https://ncbi.nlm.nih.gov/pubmed/23089195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2012.09.009
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