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Lewis acid-catalyzed intramolecular condensation of ynol ether-acetals. Synthesis of alkoxycycloalkene carboxylates

[Image: see text] Treatment of ynol ether-tethered dialkyl acetals with catalytic quantities of scandium triflate in CH(3)CN gives rise to five-, six-, and seven-membered alkoxycycloalkene carboxylates in good to excellent yields. Trisubstituted and tetrasubsituted carbocyclic and heterocyclic alken...

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Detalhes bibliográficos
Main Authors: Tran, Vincent, Minehan, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518682/
https://ncbi.nlm.nih.gov/pubmed/23170869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol303026v
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