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Protease-activated receptor-1 modulates hippocampal memory formation and synaptic plasticity

Protease-activated receptor-1 (PAR1) is an unusual G-protein coupled receptor (GPCR) that is activated through proteolytic cleavage by extracellular serine proteases. While previous work has shown that inhibiting PAR1 activation is neuroprotective in models of ischemia, traumatic injury, and neuroto...

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Hlavní autoři: Almonte, Antoine G., Qadri, Laura H., Sultan, Faraz A., Watson, Jennifer A., Mount, Daniel J., Rumbaugh, Gavin, Sweatt, J. David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518655/
https://ncbi.nlm.nih.gov/pubmed/23113835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12075
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