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Two-photon optogenetics of dendritic spines and neural circuits in 3D
We demonstrate a two-photon optogenetic method that generates action potentials in neurons with single-cell precision, using the red-shifted opsin C1V1(T). We apply the method to optically map synaptic circuits in mouse neocortical brain slices and to activate small dendritic regions and individual...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518588/ https://ncbi.nlm.nih.gov/pubmed/23142873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2249 |
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