MASS SPECTROMETRY-BASED IDENTIFICATION OF NATIVE CARDIAC Nav1.5 CHANNEL α SUBUNIT PHOSPHORYLATION SITES

Cardiac voltage-gated Na(+) (Nav) channels are key determinants of action potential waveforms, refractoriness and propagation, and Nav1.5 is the main Nav pore-forming (α) subunit in the mammalian heart. Although direct phosphorylation of the Nav1.5 protein has been suggested to modulate various aspe...

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Hauptverfasser: Marionneau, Céline, Lichti, Cheryl F, Lindenbaum, Pierre, Charpentier, Flavien, Nerbonne, Jeanne M, Townsend, R Reid, Mérot, Jean
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518584/
https://ncbi.nlm.nih.gov/pubmed/23092124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr300702c
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