Retrograde Changes in Presynaptic Function Driven by Dendritic mTORC1

Mutations that alter signaling through the mammalian target of rapamycin complex 1 (mTORC1), a well established regulator of neuronal protein synthesis, have been linked to autism and cognitive dysfunction. Although previous studies have established a role for mTORC1 as necessary for enduring change...

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Главные авторы: Henry, Fredrick E., McCartney, Amber J., Neely, Ryan, Perez, Amanda S., Carruthers, Cynthia J. L., Stuenkel, Edward L., Inoki, Ken, Sutton, Michael A.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518308/
https://ncbi.nlm.nih.gov/pubmed/23197706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2149-12.2012
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