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Linking abnormal mitosis to the acquisition of DNA damage

Cellular defects that impair the fidelity of mitosis promote chromosome missegregation and aneuploidy. Increasing evidence reveals that errors in mitosis can also promote the direct and indirect acquisition of DNA damage and chromosome breaks. Consequently, deregulated cell division can devastate th...

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Detalhes bibliográficos
Main Authors: Ganem, Neil J., Pellman, David
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518222/
https://ncbi.nlm.nih.gov/pubmed/23229895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201210040
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