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Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells
In this paper, we describe how a dynamic regulatory process is necessary to restrict microvilli to the apical aspect of polarized epithelial cells. We found that local phosphocycling regulation of ezrin, a critical plasma membrane–cytoskeletal linker of microvilli, was required to restrict its funct...
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| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518218/ https://ncbi.nlm.nih.gov/pubmed/23209304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201207047 |
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