Downregulation of Cyclophilin A by siRNA diminishes non-small cell lung cancer cell growth and metastasis via the regulation of matrix metallopeptidase 9

BACKGROUND: Cyclophilin A (CypA) is a cytosolic protein possessing peptidyl-prolyl isomerase activity that was recently reported to be overexpressed in several cancers. Here, we explored the biology and molecular mechanism of CypA in non-small cell lung cancer (NSCLC). METHODS: The expression of Cyp...

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Autori principali: Qian, Zhe, Zhao, Xiaoting, Jiang, Mei, Jia, Wenyun, Zhang, Chunyan, Wang, Yue, Li, Baolan, Yue, Wentao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518206/
https://ncbi.nlm.nih.gov/pubmed/23031673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-442
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