Quantification of minimal residual disease (MRD) in acute lymphoblastic leukemia (ALL) using amplicon-fusion-site polymerase chain reaction (AFS-PCR)

The amplification of putative oncogenes is a common finding within the genome of various cancer types. Identification and further targeting of specific junction sites within the sequence of genomic amplicons (amplicon fusion sites, AFS) by PCR (AFS-PCR) is suitable for quantification of minimal resi...

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Main Authors: Weber, Axel, Taube, Sylvia, zur Stadt, Udo, Horstmann, Martin, Krohn, Knut, Bradtke, Jutta, Teigler-Schlegel, Andrea, Leiblein, Sabine, Christiansen, Holger
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518178/
https://ncbi.nlm.nih.gov/pubmed/23210797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2162-3619-1-33
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