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Temporal Profiling of Lapatinib-suppressed Phosphorylation Signals in EGFR/HER2 Pathways
Lapatinib is a clinically potent kinase inhibitor for breast cancer patients because of its outstanding selectivity for epidermal growth factor receptor (EGFR) and EGFR2 (also known as HER2). However, there is only limited information about the in vivo effects of lapatinib on EGFR/HER2 and downstrea...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The American Society for Biochemistry and Molecular Biology
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518135/ https://ncbi.nlm.nih.gov/pubmed/22964224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.019919 |
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