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Large-scale Discovery of Substrates of the Human Kinome

Kinase networks are important for cellular signal transduction. Despite tremendous efforts to uncover these signaling pathways, huge numbers of uncharacterized phosphosites still remain in the human proteome. Because of the transient nature of kinase-substrate interactions in vivo, it is almost impo...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Sugiyama, Naoyuki, Imamura, Haruna, Ishihama, Yasushi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642169/
https://ncbi.nlm.nih.gov/pubmed/31324866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46385-4
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