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Large-scale Discovery of Substrates of the Human Kinome

Kinase networks are important for cellular signal transduction. Despite tremendous efforts to uncover these signaling pathways, huge numbers of uncharacterized phosphosites still remain in the human proteome. Because of the transient nature of kinase-substrate interactions in vivo, it is almost impo...

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Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Sugiyama, Naoyuki, Imamura, Haruna, Ishihama, Yasushi
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642169/
https://ncbi.nlm.nih.gov/pubmed/31324866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46385-4
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