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Methionine-Restricted C57BL/6J Mice Are Resistant to Diet-Induced Obesity and Insulin Resistance but Have Low Bone Density

Dietary methionine restriction (MR) extends lifespan, an effect associated with reduction of body weight gain, and improvement of insulin sensitivity in mice and rats as a result of metabolic adaptations in liver, adipose tissue and skeletal muscle. To test whether MR confers resistance to adiposity...

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Autori principali: Ables, Gene P., Perrone, Carmen E., Orentreich, David, Orentreich, Norman
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518083/
https://ncbi.nlm.nih.gov/pubmed/23236485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051357
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