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A Link between Autophagy and the Pathophysiology of LRRK2 in Parkinson's Disease

Parkinson's disease is a debilitating neurodegenerative disorder, and its molecular etiopathogenesis remains poorly understood. The discovery of monogenic forms has significantly advanced our understanding of the molecular mechanisms underlying PD, as it allows generation of cellular and animal...

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Autors principals: Gómez-Suaga, Patricia, Fdez, Elena, Blanca Ramírez, Marian, Hilfiker, Sabine
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518055/
https://ncbi.nlm.nih.gov/pubmed/23251830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/324521
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