Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability

The paraneoplastic neurologic disorders target several families of neuron-specific RNA binding proteins (RNABPs), revealing that there are unique aspects of gene expression regulation in the mammalian brain. Here we used HITS-CLIP to determine robust binding sites targeted by the neuronal Elav-like...

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Autors principals: Ince-Dunn, Gulayse, Okano, Hirotaka James, Jensen, Kirk, Park, Woong-Yang, Ru, Zhong, Ule, Jernej, Mele, Aldo, Fak, Jak, Yang, ChingWen, Zhang, Chaolin, Yoo, Jong, Herre, Margaret, Okano, Hideyuki, Noebels, Jeffrey L., Darnell, Robert B.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517991/
https://ncbi.nlm.nih.gov/pubmed/22998874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.07.009
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