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Effective antibody therapy induces host-protective antitumor immunity that is augmented by TLR4 agonist treatment

Toll-like receptors are potent activators of the innate immune system and generate signals leading to the initiation of the adaptive immune response that can be utilized for therapeutic purposes. We tested the hypothesis that combined treatment with a Toll-like receptor agonist and an antitumor mono...

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Detalhes bibliográficos
Main Authors: Wang, Shangzi, Astsaturov, Igor A., Bingham, Catherine A., McCarthy, Kenneth M., von Mehren, Margaret, Xu, Wei, Alpaugh, R. Katherine, Tang, Yong, Littlefield, Bruce A., Hawkins, Lynn D., Ishizaka, Sally T., Weiner, Louis M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517883/
https://ncbi.nlm.nih.gov/pubmed/21842208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-1090-7
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